Yesterday I went with a friend to see this amazing exhibit of the work of Joseph Cornell. http://www.sfmoma.org/exhibitions/exhib_detail.asp?id=264
I found his work, and the info about his life, to be extremely moving and inspiring. One thing I didn't know was that Cornell's brother Robert, who had severe cerebral palsy lived with him towards the end of his (Robert's) life.
If you are going to be anywhere near the Bay Area while the exhibition is on, I highly recommend it!